Microdosing candies linked to seizures, intubation finally recalled

It's not a food product; it's classified as a supplement. Foods and drugs are regulated, supplements aren't, thanks to some heavy duty lobbying.
Yep, and don't expect this congress and absolutely not this Supreme Court to even think about trying to regulate it.
 
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A Company You Can Trust​

Founded in 2016, our company has rapidly emerged as a seasoned player in the industry, boasting a deep understanding of its intricacies. Over the years, we’ve honed our expertise and cultivated an unparalleled knowledge of the market, enabling us to navigate its ever-evolving landscape with confidence. Our product lines have withstood the test of time, having been meticulously developed and rigorously tested, ensuring that they consistently deliver on their promises. With a track record of success and a commitment to innovation, we continue to set the standard for excellence, providing our customers with the reliability and quality they’ve come to expect from a company that truly knows the ins and outs of the industry.
So, no mention of safety.
What they mainly seem to be bragging about is:
a deep understanding of the industry,
unparalleled knowledge of the market,
product lines that deliver on time,
track record of success,
knows the in and outs of the industry.

In other words, "You can trust us to make money selling this"
 
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On the other hand, if you had told me as a teen in '90s small town Georgia that one day I would be sitting in the waiting room of a pot shop reading about 'shroom chocolate recalls...
You (and I) would be thinking, "Wow it's going to be so enlightened in the future!"
However........
 
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CLIA-certified labs do not issue CoA's. The "CL" stands for 'Clinical Laboratory. You are correct - clinical labs are tightly and closely regulated (unless you're Theranos), but they specifically analyze clinical samples. Clinical samples are blood, urine, plasma, etc. samples from humans. They're not involved in or responsible for any type of product release testing.

Any company can issue a "CoA." Basically a company sets specifications for a product, and each manufactured batch is analyzed to see if it conforms to the specifications. The method used for a specific analysis can be an 'official' method by a standards organization (e.g., USP, AOAC, AOCS, etc.), or an 'in-house' method clearly described in an SOP.

The amount of oversight and auditing of labs issuing CoAs depends on the intended use of the product. Drugs manufactured for human use must be manufactured under GMP conditions, and the labs analyzing these products must function under GLP. GMP and GLP facilities are subject to surprise government inspections and audits. And with regulations come added expense.

As for 'supplements,' the overwhelming majority of manufacturers of 'supplements' are not going to incur the added expense of using a GLP-certified lab. Why would they? They're not regulated. I wouldn't be surprised to find that DiamondShruumz is using Joe's Analytical and Upholstery Cleaning Services.
Joe: "I'm not only a tester, I'm also a client."
 
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Plasmodia Drywall

Smack-Fu Master, in training
59
Subscriptor++
Diphenhydramine does the same sort of thing (warning recreational dosage is close to lethal. Don't try without extensive research). It was... Fucking. Insanity.

I was in the bathroom and a small bump grew on the wall and spiders started to crawl out of it and it was just a fact. Okay there are spiders there now. I then went into the living room and sat on the couch and a friend I hadn't seen in about twenty years walked into the room and we had a full conversation for a good minute. I blinked and they were gone. I couldn't remember who it was or what we talked about. Nothing about this was abnormal at all. I could not tell I was hallucinating. I could not tell that my consciousness was altered in any way. Nothing. It was reality. Period.

I have never experienced such absolutism with a psychedelic. Even when your brain is completely smeared across the universe, something inside you knows that things aren't supposed to be quite this way. It was not the case with diphenhydramine.
Sounds like Jimson weed
 
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POSIX

Seniorius Lurkius
29
Subscriptor++
Blows my mind that a company poisons its customers and it's up to them to decide whether and when to issue a recall
I suspect this recall was less than voluntary. There's now been several lab reports showing problems that have made the news. I'm guessing they realized that the FDA was getting close to having the paperwork ready for ordering a recall and tried essentially a "you can't fire me, I quit" maneuver as spin and damage control. If their hand hadn't been about to be forced, I bet they'd still be selling them. They haven't shown any concern for their customers up to this point, why would they start now?
 
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Muscimol, ibotenic acid, 4-AcO-DMT, and kava. If it has all these things in it, it looks like it was made to injure and kill people. For having all that in it, it's obvious that it's way beyond processing contamination. Not to mention that if you took all of those together, you're going to have a psychedelic experience, which may be the worst and most powerful trip of all trips. It's wretched it is to have a trip you didn't plan. Some people are not aware of the trendy buzzwords and truly think it's a dietary benefit to take them.

Muscimol is terrible, if you survive it. In fact, they feed amanita mushrooms to reindeer and after it's processed, they drink the urine. This action is supposed to make it safer, and of course, more disgusting. It messes up your dreams, causes drooling, and people say it's more like being drunk than tripping.

According to some brief research I did, the product in question is made by a company called Prophet Premium Blends in Newport Beach and Santa Ana, CA. I'm not sure where their labs, vendors, or manufacturing facilities are, but in California, these chemicals are not just dangerous, they're mostly illegal. Some are not federally banned, but are banned by state, county, and/or municipality.
 
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I understand if an editor says, let's not do that, but good lord do I hate the term "microdosing." It needs to be called out. It's a marketing term. Invented by an industry that smells a new revenue stream.

Near as I can tell microdosing is what we used to call on tour, "I'm taking it easy tonight."

Yer still dosed, and these are damn powerful drugs. Cannabis is as much psychedelic substance as I want to see introduced into gen pop. I can easily imagine this therapy working with intensive oversight. But that is not what any of this is about. This is about near-rec levels of availability, and then liability wavers for therapists wielding their copy of The Secret at you for 4 hours with some St. Joseph's baby psylocibin dose in your veins.

That's not gonna be therapeutic.
 
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On the other hand, if you had told me as a teen in '90s small town Georgia that one day I would be sitting in the waiting room of a pot shop reading about 'shroom chocolate recalls...

Reminds me of one of my favorite (very real!) lines from the beginning of a super serious healthcare policy meeting in DC: "I'm so glad we're bringing substance abuse back to this panel".
 
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I bought dark chocolate from Aldi recently, because I wanted to see if could make homemade chocolate brazils. It came in a pack of five bars, and when I ate one I actually found it rather bitter, though I think it will go well melted around brazil nuts. I don't really eat any sweets these last few decades, so if I find something bitter it is fucking bitter. Chocolate by itself does need a bit of sugar, I think.

A friend of mine did a stint in the Peace Corps in Panama, and then went back to live in the region. One time when he was back stateside, he brought some indigenous cacao patties. They take the cacao beans and grind them into a brownish powder, and then mix it with sugar and press it into these circles the size of small cookies.

My friend wisely advised to eat them one small bite at a time. One or two small bites is all that you need, and one of those patties probably had as much cacao as...dozens of chocolate bars, I think, maybe more?

Raw cacao powder is bitter and needs the sugar. It is also caffeinated (and other theo- xanthines) as hell. Once you've had the real thing, you understand that cacao is a drug, and what we call "chocolate" is like CBD gummies, it's extracted from a "naughty" plant, but you're mostly getting the flavor and the vibes.
 
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11 (11 / 0)
A friend of mine did a stint in the Peace Corps in Panama, and then went back to live in the region. One time when he was back stateside, he brought some indigenous cacao patties. They take the cacao beans and grind them into a brownish powder, and then mix it with sugar and press it into these circles the size of small cookies.

My friend wisely advised to eat them one small bite at a time. One or two small bites is all that you need, and one of those patties probably had as much cacao as...dozens of chocolate bars, I think, maybe more?

Raw cacao powder is bitter and needs the sugar. It is also caffeinated (and other theo- xanthines) as hell. Once you've had the real thing, you understand that cacao is a drug, and what we call "chocolate" is like CBD gummies, it's extracted from a "naughty" plant, but you're mostly getting the flavor and the vibes.

I want to add that I am not a chocoholic.

I can quit any time I want!
 
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CLIA-certified labs do not issue CoA's. The "CL" stands for 'Clinical Laboratory. You are correct - clinical labs are tightly and closely regulated (unless you're Theranos), but they specifically analyze clinical samples. Clinical samples are blood, urine, plasma, etc. samples from humans. They're not involved in or responsible for any type of product release testing.

Any company can issue a "CoA." Basically a company sets specifications for a product, and each manufactured batch is analyzed to see if it conforms to the specifications. The method used for a specific analysis can be an 'official' method by a standards organization (e.g., USP, AOAC, AOCS, etc.), or an 'in-house' method clearly described in an SOP.

The amount of oversight and auditing of labs issuing CoAs depends on the intended use of the product. Drugs manufactured for human use must be manufactured under GMP conditions, and the labs analyzing these products must function under GLP. GMP and GLP facilities are subject to surprise government inspections and audits. And with regulations come added expense.

As for 'supplements,' the overwhelming majority of manufacturers of 'supplements' are not going to incur the added expense of using a GLP-certified lab. Why would they? They're not regulated. I wouldn't be surprised to find that DiamondShruumz is using Joe's Analytical and Upholstery Cleaning Services.

Thanks, lab and pharmacy stuff is just adjacent-enough to find my way around, but every time I'm reminded that there are entire universes of regs that I haven't had to touch yet.

But yeah, assuming that the acetyl psilocyn analogue was flagged by a lab that someone expected to introduce into evidence in court, and unless Daubert has been Chevroned* as well, that still seems like the most legitimate findings.

Unless it was the DEA. That's the one thing that does worry me, I'm the last person to suggest any government conspiracy, but the DEA is a different beast, it's what the CIA would have become if GHWB hadn't cleaned out Nixon's corruption there under Ford. The DEA could absolutely just claim the candies contained whatever C-I drug is most convenient.


*Yeah, I'm just slightly bitter about this recent decision
 
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nikakd

Smack-Fu Master, in training
80
Holy crap! That's the infamous fly agaric mushroom. Not necessarily deadly, but definitely not a pleasant experience when eaten. Bet these guys were going around without an experienced mushroom hunter and picking mushrooms that look vaguely like Psilocybin mushrooms. Looks close enough, riiiight?!
No one, no matter how inexperienced, could ever mix up amanita muscaria, with a large flat red cap with white dots, witn psylocibin mushrooms, that are much smaller, brown and conical
 
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Suspiciously sounding more AI generated or copied from other sources with every word. Throwing in something something synergy would also not be out of place.
It reads to me as the most copy-ass copy ever written. I've known professional copy writers, that's a lingo bingo checklist if I've ever seen one.
 
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ARS_dabbler

Ars Praetorian
582
Subscriptor++
Holy crap! That's the infamous fly agaric mushroom. Not necessarily deadly, but definitely not a pleasant experience when eaten. Bet these guys were going around without an experienced mushroom hunter and picking mushrooms that look vaguely like Psilocybin mushrooms. Looks close enough, riiiight?!
The Fly Agaric and the Psilocybin look nothing alike! First image Psilocybin.
Second image Fly Agaric
Psilocybin.pngFly Agaric.png
 
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4 (5 / -1)
I don't hear people say that as much as I used to, but it always makes me chuckle when I do. Cobra venom is natural. Poison Ivy is natural. Magnitude 8 earthquakes are natural. The proof by contradiction seems pretty straightforward to me.
Well at least it doesn't contain any chemicals.
 
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Mindstatic

Ars Scholae Palatinae
4,928
Subscriptor
You (and I) would be thinking, "Wow it's going to be so enlightened in the future!"
However........
Right?!?
The day I walk into a 7/11 and buy a pack of Marlboro Mentholated Joints is probably the day I'll finally quit and take up my life-long dream of heroin addicted ballroom dancing.
 
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I'm confused about why you would be eating a Diamond Shruumz candy bar if you were just expecting some chocolate.
Because I am 6-years old and I love chocolate and I love gummy bears. It is chocolate and wrapped in a childish package. No adult would make something like that if it was dangerous for me, right? Right?

Wow, mom sure has been asleep for a long time.


edit: I enjoy mushrooms. I enjoy candy. Stop being an idiot and putting mushrooms IN candy.
 
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A friend of mine did a stint in the Peace Corps in Panama, and then went back to live in the region. One time when he was back stateside, he brought some indigenous cacao patties. They take the cacao beans and grind them into a brownish powder, and then mix it with sugar and press it into these circles the size of small cookies.

My friend wisely advised to eat them one small bite at a time. One or two small bites is all that you need, and one of those patties probably had as much cacao as...dozens of chocolate bars, I think, maybe more?

Raw cacao powder is bitter and needs the sugar. It is also caffeinated (and other theo- xanthines) as hell. Once you've had the real thing, you understand that cacao is a drug, and what we call "chocolate" is like CBD gummies, it's extracted from a "naughty" plant, but you're mostly getting the flavor and the vibes.
I still remember "stealing" some raw cacao powder from my grandma when she was baking, and mixing it up with some butter on a spoon. Yum!
 
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orwelldesign

Ars Tribunus Angusticlavius
6,072
Subscriptor++
I've been writing a novel about a young woman with schizophrenia and wanting to treat her illness with respect and realism. I'd be willing to try this to help understand her better.

Strong recommend against.

If you want to know, really know, what it's like to live with a mental illness, go take some Lithium. The anti-schiz drugs all do the same sort of thing: they make it so you're going through life wearing a rubber suit ten feet thick. Can't feel anything, except as pressure. They dampen everything hard so that reality is tolerable and tolerably real.

I had a schizophrenic roommate for a while (we all met in rehab, and as my wife and I got our shit together, we couldn't watch them be homeless) and it was enlightening. He knew the voices in his head weren't real, but he still talked to them frequently. One of my most vivid memories of him was him doing the dishes and arguing with the voices: "Hey, go away, we're just doing the dishes." And he spent twenty minutes telling the voices in his head "no, you need to hold up, we've got dishes to do." Singing to himself, dancing a little bit.

But the dishes got done.
 
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They don't list the ingredients? Over in the other side of the world all food products have to list ingredients and nutritional information...
You can thank Oren Hatch and the Mormon church backed supplement grift.
If you call it a supplement you can get away with selling things that don’t even contain a trace of the “supplement”. It’s just another example of regulatory capture in the US
 
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panton41

Ars Legatus Legionis
10,558
Subscriptor
Strong recommend against.

If you want to know, really know, what it's like to live with a mental illness, go take some Lithium. The anti-schiz drugs all do the same sort of thing: they make it so you're going through life wearing a rubber suit ten feet thick. Can't feel anything, except as pressure. They dampen everything hard so that reality is tolerable and tolerably real.

I had a schizophrenic roommate for a while (we all met in rehab, and as my wife and I got our shit together, we couldn't watch them be homeless) and it was enlightening. He knew the voices in his head weren't real, but he still talked to them frequently. One of my most vivid memories of him was him doing the dishes and arguing with the voices: "Hey, go away, we're just doing the dishes." And he spent twenty minutes telling the voices in his head "no, you need to hold up, we've got dishes to do." Singing to himself, dancing a little bit.

But the dishes got done.
I have bipolar II and recently had a bought of missing enough medication for it to come through.

Lithium carbonate is an indicator for bipolar because if you don't have it, then it does nothing, but if you do then it can stabilize your mood. These days, though, it's generally considered obsolete due to extremely dangerous side effects, but its low cost keeps it in use. (A 60-pill, 300mg supply at Walmart is $4 retail, but taking 1200mg a day wasn't uncommon when I took it as a middle schooler.)

It is literally lithium ore and mined out of the ground. Places that naturally have high lithium in their groundwater also have lower rates of crime, suicide and other sociological indicators of poor mental health.
 
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I have bipolar II and recently had a bought of missing enough medication for it to come through.

Lithium carbonate is an indicator for bipolar because if you don't have it, then it does nothing, but if you do then it can stabilize your mood. These days, though, it's generally considered obsolete due to extremely dangerous side effects, but its low cost keeps it in use. (A 60-pill, 300mg supply at Walmart is $4 retail, but taking 1200mg a day wasn't uncommon when I took it as a middle schooler.)

It is literally lithium ore and mined out of the ground. Places that naturally have high lithium in their groundwater also have lower rates of crime, suicide and other sociological indicators of poor mental health.
The good thing is that if you run out of pills, you can just lick your EV battery.
 
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mode1charlie

Ars Centurion
329
Subscriptor
Why is this company - or at least its product lines at issue - not immediately shut down by the FDA? If it were selling products with pathogens that caused consumers to be intubated, people would be screaming bloody murder. But somehow it's ok to keep selling its goods because they're "natural substances"? Absurd.
 
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migrena

Wise, Aged Ars Veteran
131
Holy crap! That's the infamous fly agaric mushroom. Not necessarily deadly, but definitely not a pleasant experience when eaten. Bet these guys were going around without an experienced mushroom hunter and picking mushrooms that look vaguely like Psilocybin mushrooms. Looks close enough, riiiight?!
i mean... you need to be very much legally blind to mistake one for another. below are comparison pictures (and it took me quite a while to find ones that do resemble each other a bit). let me repeat this again - they were adding other "medicinal" (as in not psychoactive but with dubious health benefit claims) mushrooms. most likely poor quality control of their sourcing for material that gets easily contaminated during production and storage ("boss this red mushroom fell into the container what should i do? eh, we are not wasting whole container of lion's mane, it's fine, ship it.") resulted in some amounts of unwanted chemicals in their confectionery. they tried to cover their asses by doing some amount of testing but the quality of them is questionable. i pointed this in previous article and Beth mentioned it now too. sadly the most likely shruumz will go under without any serious consequences and prophet belnds will just rebrand it to another product. supplements regulation is a joke, not only in usa but in other countries as well.
ynews-270466913.jpg

Amanita-Muscaria-7.jpg
 
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migrena

Wise, Aged Ars Veteran
131
If you're experienced with these types of products you know not to eat the whole package at one time. There may be potency issues, but there are also failure to heed the label issues, too. This also happens with products bought at legitimate dispensaries.
those products were not supposed to contain muscimol or any other psychoactive alcaloid found in mushrooms for that matter. those products were even tested for that. there is no "potency issues". so you know where you can stick your argument in.
i would question intelligence of anyone buying this kind of products, no problem, but this is not the issue here.
 
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migrena

Wise, Aged Ars Veteran
131
As the article notes, previous COAs showed undetectable levels of muscimol. If those COAs were from CLIA-certfied labs, they're accurate or those labs are in deeper shit than any mushroom could dream of: CLIA is overseen by CMS, and if the Jaws theme isn't playing in your head at that acronym, then you don't work in medicine.

So I'm going to take the word of CLIA-certified lab COAs and whatever government lab found 4-Aco-DMT in these candies, over the word of executives desperate for a regulatory violation because the CSA is one of the few criminal laws less friendly to defendants than regulatory law.
the issue is the lack of regulation of supplements. there is no real information how often products were tested, how they were sampled etc. for what we know they might have been tested once, or multiple times until the results were satisfactory... so all that was done seem to be mostly voluntary tests by the brand company.
on the other hand i spotted typos (fortunately inconsequential ones) in the reports and i'm not a trained chemist so the quality of the data might not be great too.
 
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They're not inspected by the FDA, so of course they can't really be held to GLP and GMPs by the FDA. If not FDA, is there any regulation at the state or local level?

The main thing motivating the third party lab is continued employment by Diamond Shruumz/Prophet, at least until somebody gets hurt. We certainly can't assume anything about the third party lab's analytical method validation, like the limit of quantitation of the test method. LoD/LoQ are often arbitrary, but should be set well below an actual limit that we either know could cause harm, or simply at a level that alerts the manufacturer that something's out of trend with the manufacturing process that should be investigated (way before harm). Also, that lab doesn't appear to be performing any microbiological testing, based on the CoA. Is there another lab contracted for that, and would they know what to test for? There's no guarantee of anything without regulatory inspection of the methods. Edit: The ACS lab does have reassuring certifications, but are they testing the right things at the right frequency and specification for this manufacturer's products?

There's no guarantee the product is a homogeneous mixture without regulatory inspection of the manufacturing facilities and methods., This means there could easily be variation in contaminant levels both within and between lots of product. There could be variations between product produced on first or third shift. How often do deviations happen? What percentage of lots are tested? Are samples of any lots held back for stability testing? What's in the chocolate after a year on the shelf, or in a warehouse that isn't air-conditioned?

The TLDR; We don't seem to know how this stuff is made, tested, shipped or stored. Making safe, unadulterated food and drugs is difficult to get right even with regulatory inspections. The big players still sometimes screw it up, but with actual regulation the chances of, well, not hurting people, go way up.
 
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SplatMan_DK

Ars Tribunus Angusticlavius
7,794
Subscriptor++
I don't hear people say that as much as I used to, but it always makes me chuckle when I do. Cobra venom is natural. Poison Ivy is natural. Magnitude 8 earthquakes are natural. The proof by contradiction seems pretty straightforward to me.
Cobra venon and Poison ivy are complex molecules with complex effects.

When someone gives me the "it's natural" story, I usually go with Arsenic, Mercury or Plutonium.
 
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