I've had my 16 for about a month, and have been satisfied so far.
Purchase
I suggest getting the DIY Edition, as I saved money buying RAM elsewhere ($220 vs $400, 64GiB).
Setup
Even if you get the DIY Edition, it's mostly pre-assembled (boo!). The only problem I had was assembling the touchpad: I think the 16 shares the same touchpad with the 13, because there are spacers to make it fit. It took me two days, and 5-10 attempts, before I got all three lined up properly. I think it's a matter of poor design; reshaping the pieces helped them fit. The build quality is equal to that of any other vendor I've experienced, the laptop is pretty solid.
I went with Win11, installed from the Media Creation Tool. Win11 doesn't have the drivers for the network card, and this will prevent installation. The way to bypass this is to open the Command Prompt with Shift + F10, type "OOBE\BYPASSNRO", press Enter, then reboot. It will proceed to the network installation page, but presents a new option: "I don’t have internet". Select that and you're all set.
Firmware and drivers were straightforward, so whatever problems existed appear to be dealt with. No BSODs, either.
Use
Battery life is OK, around 4-6 hours of light usage. Battery drain while asleep is a problem, but Windows deals with this by putting the system into hibernation.
When putting the system to sleep, I find it's best to unplug the power first. Unplugging the power wakes my system up.
While asleep, the system appears to leave bluetooth and wireless connections on (probably due to Windows Modern Standby).
The system is generally quiet, as long as you aren't using the dGPU. When gaming, you;re better off wearing headphones, the fans are loud, and there are no fan controls. I recommend buying the expansion bay with the dGPU, if you plan on using the dGPU sparingly.
The power cord is very much appreciated. Instead of a brick at the plug end, it's just a plug. No worries about blocking other plugs, and this makes it easier to reach less accessable outlets.